Colombia GuideColombia — forget the reputation. Twice the size of France, and with a diversity of landscapes and cultures that would be hard to find even in countries five times its size, Colombia belongs in the upper echelons of the world's most incredible travel destinations. HotelsFind hotels in Bogota, Medellin, Cartagena de Indias, Cali and more. BogotáBogotá's sheer size and violent reputation are intimidating for visitors, but the city opens up to the savvy traveler with incredible riches befitting the capital of Colombia, and one of the biggest cities in Latin America. MedellínMedellín is the second largest city in Colombia. It has over 2 million people and is the capital of the department of Antioquia. CartagenaCartagena is a city in Bolívar, Colombia. The city was one of the first sanctuaries of freed African slaves in the Americas and is currently populated by an ethnic mix representative of Colombia's own variety. AndinoThe Andean Highlands is a region in central-western Colombia. Since Spanish is the official language of Colombia, it should be relatively easy to get around in the larger cities knowing basic Spanish. Costa NorteThe Caribbean Lowlands is a region in northern Colombia. One of the best ways to see the southernmost Caribbean islands or surrounding South American islands is via a cruise. PacificaThe Pacific Lowlands is a region in western Colombia. Tumaco, Buenaventura, Quibdo, Nuqui, Barbacoas, Guapi, Timbiqui, Bahia Solano, Cali, Buga OrinoquíaThe Eastern Plains is a region in Colombia. Colombian IslandsColombia has several island territories in the Carribean: AmazoniaAmazonia is the rainforest region in the south of Colombia. While short on movie theaters and golf courses, the Colombian Amazon has its fair share of possibilities for outdoor activities. GuatapeGuatapé is a small, very pretty lakeside town in Eastern Antioquia, about 1.5 hours from Medellín, Colombia.