Eastern Oregon GuideEastern Oregon is the eastern portion of Oregon which is arid and sparsely inhabited. Much of it is desert and semi-desert. It covers between a third and a half of the state's land area. HotelsFind hotels in Joseph, Boardman, Baker City and more. Harney CountyHarney County is in the High Desert region of Oregon. Much of Harney's population comes from the rural towns and surrounding areas of Crane, Drewsey, Frenchglen, and Riley. JosephJoseph is a city in Eastern Oregon at an elevation of 4,150 feet above sea level. BoardmanBoardman is in North Eastern Oregon located along the Columbia River, just east of the Columbia Gorge, and it's recreation is similar to most Gorge cities. Baker CityBaker City is a small city in Eastern Oregon located on the I-84 about 40 minutes south-east of La Grande. LakeviewLakeview is a town in eastern Oregon. It is 13 miles north of the California state line, in a region known as the Oregon Outback. PendletonPendleton is a small city in Eastern Oregon. The city is situated in a pleasant valley set among hilly cropland on the I-84 several hours east of Portland. FossilFossil is a town in Eastern Oregon. Fossil has a population of 473 as of 2010 and is the seat of Wheeler County. KimberlyKimberly is a small town in Eastern Oregon, the closest town to John Day Fossil Beds National Monument. John DayJohn Day is a city in Eastern Oregon. Milton-FreewaterMilton-Freewater is a city in Eastern Oregon. Oregon Highway 11 goes through town. OntarioOntario is a city in Eastern Oregon. La GrandeLa Grande is a city in Eastern Oregon. La Grande's slogan is "The Hub of Northeast Oregon". HermistonHermiston is a city in Umatilla County in the Eastern Oregon region of Oregon. EnterpriseEnterprise is a city in Eastern Oregon.