Santa Catarina GuideSanta Catarina is a state in the southern region of Brazil. It is situated between Parana and Rio Grande do Sul. Grande Florianópolis North West Serrana South Itajaí Valley HotelsFind hotels in Florianopolis, Blumenau, Joinville and more. FlorianopolisFlorianopolis is the capital of the Brazilian state of Santa Catarina. Half of the city is on the mainland of Brazil while the other half is on the Santa Catarina Island. BlumenauBlumenau is a city in the Itajaí Valley, in Santa Catarina State, Southern Brazil. JoinvilleJoinville is the largest city in Santa Catarina, Brazil. It is principally an industrial city and many of its 500,000 inhabitants are of German descent. Grande FlorianópolisGrande Florianópolis is a region of the state of Santa Catarina in Southern Brazil. Itajaí ValleyThe Itajaí Valley is a region of the state of Santa Catarina in Southern Brazil. NorthNorthern Santa Catarina is a region of the state of Santa Catarina in Southern Brazil. SouthSouthern Santa Catarina is a region of the state of Santa Catarina in Southern Brazil. SerranaThe Serrana is a mountainous region of the state of Santa Catarina in Southern Brazil. WestWestern Santa Catarina is a region of the state of Santa Catarina in Southern Brazil.