Southern Maryland GuideSouthern Maryland consists of Calvert, Charles and St. Mary’s counties. Until recently, Southern Maryland's economy was fueled by tobacco and watermen. HotelsFind hotels in Lexington Park, Solomons, Lexington Park, La Plata, Prince Frederick and more. Lexington ParkLexington Park is a town on located 60 miles SSE of Washington, D.C. at the mouth of the Patuxent River in Southern Maryland. SolomonsFor the island chain in the South Pacific, see Solomon Islands. Solomons is an resort island/city located on the tip of Southern Maryland, near the Patuxent Naval Air Station, within two hours of Washington, D.C, and a convenient drive from Baltimore or Annapolis. St. Mary's CitySt. Marys City is in Southern Maryland. Despite the name, and the slogan: "Once the Metropolis of Maryland," St. La PlataLa Plata is a city in Southern Maryland. It is the county seat of Charles County. Prince FrederickPrince Frederick is a city in Southern Maryland. You'll only get to Prince Frederick by car, and MD-4 is the main road going north-south between Washington, D.C. Chesapeake BeachChesapeake Beach is in Southern Maryland. Along with North Beach, it forms a seaside community that saw its heyday before the building of the Chesapeake Bay Bridge, and the resulting competition with Ocean City, but may be experiencing a comeback. Cobb IslandCobb Island is a small town at the end of the Cobb Neck in Southern Maryland. Cobb Island lies at the southern end of the Cobb Neck in Charles County, Maryland. LeonardtownLeonardtown is a city in Southern Maryland. Leonardtown is on Route 5. About 1.5 hours from Annapolis and 1 hour from Washington D.C. WaldorfWaldorf is a city in Southern Maryland.